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Dyke-Davidoff-Masson Syndrome: A Case Report in a Filipino Male Adolescent

Received: 6 June 2022     Accepted: 6 July 2022     Published: 10 May 2023
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Abstract

A previously well young Filipino boy presented with prolonged recurrent left focal to bilateral seizure. He was born of a non-consanguineous marriage, home-delivered vaginally, full term with no perinatal complications. He had normal growth and developmental milestones until at the age of 7 months when he developed febrile status epilepticus. Since then, he was left with residual left hemiplegia, dysarthria, cognitive delay and recurrent seizures occurring twice daily. He was poorly compliant on multiple anti-seizure medications. He was able to go to school and do activities of daily living with minimal supervision from his family. Symptoms of refractory seizures, hemiparesis, facial asymmetry, and intellectual disabilities along with brain imaging evidence of cerebral hemi-atrophy with compensatory calvarial thickening and subsequent hyperpneumatization is consistent with Dyke-Davidoff-Masson Syndrome (DDMS). A rare clinico-neuroradiologic condition occurring in fetal or early childhood period as a consequence of chronic brain insult. Diagnosis is established clinically with a characteristic cranial imaging finding. Hemi-spherectomy is the treatment of choice. This case will enlighten our mind as well as aid us in the prompt recognition of this uncommon syndrome with a classic clinico-radiologic presentation. Multidisciplinary intervention is essential, primarily to optimize seizure control as well as provide quality of life.

Published in International Journal of Clinical and Experimental Medical Sciences (Volume 9, Issue 2)
DOI 10.11648/j.ijcems.20230902.11
Page(s) 21-24
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Dyke-Davidoff-Masson Syndrome (DDMS), Filipino, Adolescent

References
[1] Dyke CG, Davidoff LM, Masson CB. Cerebral hemiatrophy and homolateral hypertrophy of the skull and sinuses. Surg Gynecol Obstet 1933; 57: 588-600.
[2] Alpers BJ and Dear RB. Hemiatrophy of the brain. J Nerv Ment Dis 1939; 89: 653-651.
[3] Sharma, et al. Dyke-Davidoff Masson Syndrome Ind J Radiol Imag 2006 16: 2: 165-166.
[4] Ozkan Unala, et al. Left hemisphere and male sex dominance of cerebral hemiatrophy (Dyke Davidoff–Masson Syndrome). Journal of Clinical Imaging 28 (2004) 163-165.
[5] Amita Bhargava, et al. Dyke-Davidoff-Masson syndrome: A study of clinicoradiological variability in hemiplegia, hemiatrophy and epilepsy patients. Journal of Health and Research /Vol 1/Issue 3/ Jul-Sep 2014.
[6] Vipin Ola, et al. Dyke – Davidoff- Masson Syndrome. Journal of the association of physicians of India. January 2014, vol 62.
[7] Jun Hwa Lee et al. A case of Dyke Davidoff Masson syndrome in Korea. Korean Journal of Pediatrics Vol 49. No 2, 2006; 49: 208-211.
[8] Mehtab Alam1, et al. Dyke-Davidoff-Masson Syndrome: An Unusual Cause of Status Epilepticus and Refractory Seizures. Journal of the College of Physicians and Surgeons Pakistan 2018, Vol. 28 (Special Supplement 2 of Case Reports): S99-S101.
[9] Jitender Aneja, et al. Acquired Dyke-Davidoff-Masson syndrome (DDMS). Advanced Medical and Health Research | Volume 2, Issue 1. Jan-Jun 2015.
[10] McMonagle et al. The cognitive profile of posterior cortical atrophy. Neurology 2006; 66: 331-8.
[11] Urs, G. M., & R. Doddabele, H. (2022). Dyke-Davidoff-Masson Syndrome: A Case Report. International Journal of Medical Students, 10 (1), 82–85.
Cite This Article
  • APA Style

    Lalaine Villaflor-Oida, Rowena Cabradilla, Michelle Sy, Alejandro Bimbo Diaz, Maria Antonia Aurora Valencia. (2023). Dyke-Davidoff-Masson Syndrome: A Case Report in a Filipino Male Adolescent. International Journal of Clinical and Experimental Medical Sciences, 9(2), 21-24. https://doi.org/10.11648/j.ijcems.20230902.11

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    ACS Style

    Lalaine Villaflor-Oida; Rowena Cabradilla; Michelle Sy; Alejandro Bimbo Diaz; Maria Antonia Aurora Valencia. Dyke-Davidoff-Masson Syndrome: A Case Report in a Filipino Male Adolescent. Int. J. Clin. Exp. Med. Sci. 2023, 9(2), 21-24. doi: 10.11648/j.ijcems.20230902.11

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    AMA Style

    Lalaine Villaflor-Oida, Rowena Cabradilla, Michelle Sy, Alejandro Bimbo Diaz, Maria Antonia Aurora Valencia. Dyke-Davidoff-Masson Syndrome: A Case Report in a Filipino Male Adolescent. Int J Clin Exp Med Sci. 2023;9(2):21-24. doi: 10.11648/j.ijcems.20230902.11

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  • @article{10.11648/j.ijcems.20230902.11,
      author = {Lalaine Villaflor-Oida and Rowena Cabradilla and Michelle Sy and Alejandro Bimbo Diaz and Maria Antonia Aurora Valencia},
      title = {Dyke-Davidoff-Masson Syndrome: A Case Report in a Filipino Male Adolescent},
      journal = {International Journal of Clinical and Experimental Medical Sciences},
      volume = {9},
      number = {2},
      pages = {21-24},
      doi = {10.11648/j.ijcems.20230902.11},
      url = {https://doi.org/10.11648/j.ijcems.20230902.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20230902.11},
      abstract = {A previously well young Filipino boy presented with prolonged recurrent left focal to bilateral seizure. He was born of a non-consanguineous marriage, home-delivered vaginally, full term with no perinatal complications. He had normal growth and developmental milestones until at the age of 7 months when he developed febrile status epilepticus. Since then, he was left with residual left hemiplegia, dysarthria, cognitive delay and recurrent seizures occurring twice daily. He was poorly compliant on multiple anti-seizure medications. He was able to go to school and do activities of daily living with minimal supervision from his family. Symptoms of refractory seizures, hemiparesis, facial asymmetry, and intellectual disabilities along with brain imaging evidence of cerebral hemi-atrophy with compensatory calvarial thickening and subsequent hyperpneumatization is consistent with Dyke-Davidoff-Masson Syndrome (DDMS). A rare clinico-neuroradiologic condition occurring in fetal or early childhood period as a consequence of chronic brain insult. Diagnosis is established clinically with a characteristic cranial imaging finding. Hemi-spherectomy is the treatment of choice. This case will enlighten our mind as well as aid us in the prompt recognition of this uncommon syndrome with a classic clinico-radiologic presentation. Multidisciplinary intervention is essential, primarily to optimize seizure control as well as provide quality of life.},
     year = {2023}
    }
    

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    AU  - Lalaine Villaflor-Oida
    AU  - Rowena Cabradilla
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    JF  - International Journal of Clinical and Experimental Medical Sciences
    JO  - International Journal of Clinical and Experimental Medical Sciences
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    UR  - https://doi.org/10.11648/j.ijcems.20230902.11
    AB  - A previously well young Filipino boy presented with prolonged recurrent left focal to bilateral seizure. He was born of a non-consanguineous marriage, home-delivered vaginally, full term with no perinatal complications. He had normal growth and developmental milestones until at the age of 7 months when he developed febrile status epilepticus. Since then, he was left with residual left hemiplegia, dysarthria, cognitive delay and recurrent seizures occurring twice daily. He was poorly compliant on multiple anti-seizure medications. He was able to go to school and do activities of daily living with minimal supervision from his family. Symptoms of refractory seizures, hemiparesis, facial asymmetry, and intellectual disabilities along with brain imaging evidence of cerebral hemi-atrophy with compensatory calvarial thickening and subsequent hyperpneumatization is consistent with Dyke-Davidoff-Masson Syndrome (DDMS). A rare clinico-neuroradiologic condition occurring in fetal or early childhood period as a consequence of chronic brain insult. Diagnosis is established clinically with a characteristic cranial imaging finding. Hemi-spherectomy is the treatment of choice. This case will enlighten our mind as well as aid us in the prompt recognition of this uncommon syndrome with a classic clinico-radiologic presentation. Multidisciplinary intervention is essential, primarily to optimize seizure control as well as provide quality of life.
    VL  - 9
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Author Information
  • University of Santo Tomas Hospital, Manila, Philippines

  • University of Santo Tomas Hospital, Manila, Philippines

  • University of Santo Tomas Hospital, Manila, Philippines

  • University of Santo Tomas Hospital, Manila, Philippines

  • University of Santo Tomas Hospital, Manila, Philippines

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