| Peer-Reviewed

Post-Traumatic Epilepsy: A Review of This Pathology in Childhood

Received: 23 February 2022     Accepted: 24 March 2022     Published: 13 July 2022
Views:       Downloads:
Abstract

Introduction: Traumatic brain injury has been related to the 20% of symptomatic epilepsy in the general population; In children, information about the magnitude of this condition is few, because the occurrence can develop in immediate periods or even years after the injury. Objective: To evaluate the epidemiological and clinical characteristics in pediatric patients diagnosed with Post-Traumatic Epilepsy. Methods: Children's Records diagnosed with post-traumatic epilepsy from the Pediatric Neurology Service. The clinical-epidemiological characteristics of the trauma, the convulsive crisis and the latency period in its presentation were identified. The difference of quantitative variables was estimated to evaluate their association, according to the intensity of the Head Traumatism (TBI). Results: 72 children with an average age of 8.7 years and males predominance of with 65.3% were included. The most frequent traumatic brain injury site (TBI) was occipital with 35.6% and the classification was 47.6% for mild. 93.1% presented simple partial crisis and 73.6% of children had neurological sequelae. The median onset for the epileptic seizure was 2.9 years, this period being shorter in relation to the intensity of the trauma and the age group in which it occurs. Conclusions: There is a clinical correlation between the intensity of TBI with the acute presence of epilepsy. It is necessary for the community of neurologists to develop follow-up protocols focused on informing and providing adequate care to patients at high risk of presenting post-traumatic epilepsy, including providing information to parents in a timely manner of this risk considering the intensity of the TBI and without ruling out those who suffered mild TBI.

Published in International Journal of Clinical and Experimental Medical Sciences (Volume 8, Issue 4)
DOI 10.11648/j.ijcems.20220804.11
Page(s) 50-55
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Post-Traumatic Epilepsy, Head Injury, Convulsive Crisis, Pediatric Neurology

References
[1] Garga N, Lowenstein DH. Postraumatic epilepsy: A major problem in desperate need of major advances. Epilepsy Curr. 2006; 6 (1): 1-5.
[2] Agrawal A, Timothy J, Pandit L, Manju M. Post-traumatic epilepsy: an overview. Clinical neurology and neurosurgery. 2006; 108 (5): 433-9.
[3] De Villegas C, Salazar J. Traumatismo cráneo encefálico en niños. Revista de la Sociedad Boliviana de Pediatría. 2008; 47 (1): 19-29.
[4] Galarza MA, Valdés WM, Alatorre AGG, Gallego CI. Traumatismo craneoencefálico grave en pacientes pediátricos. Factores pronósticos de mortalidad. Medicina Universitaria. 2008; 10 (38): 16-21.
[5] Schwartzkroin PA. Getting a scientific paper published in Epilepsia: An editor's perspective. Epilepsia. 2013; 54 (11): 1852-4.
[6] Fisher RS, Acevedo C, Arzimanoglou A, et al. A practical clinical definition of epilepsy. International League Against Epilepsy Official Report. Epilepsia 2014; 55 (4): 475–482.
[7] Izquierdo AY. Crisis convulsivas. Concepto, clasificación y etiología. emergencias. 2005; 17: S68-S73.
[8] De la Peña P, Porta-Etessam J. Epilepsia postraumática. Rev Neurol. 1998; 26: 256-61.
[9] Frey LC. Epidemiology of posttraumatic epilepsy: a critical review. Epilepsia. 2003; 44 (s10): 11-7.
[10] Mercadé Cerdá J, Toledo Argani M, Mauri Llerda J, López Gonzalez F, Salas Puig X, Sancho Rieger J. Guía oficial de la Sociedad Española de Neurología de práctica clínica en epilepsia. Neurología. 2014.
[11] Kouloulas EJ, Papadeas AG, Michail X, Sakas DE, Boviatsis EJ. Prognostic value of time-related Glasgow Coma Scale components in severe traumatic brain injury: a prospective evaluation with respect to 1-year survival and functional outcome. International Journal of Rehabilitation Research. 2013; 36 (3): 260-7.
[12] Mondragón LB, Ramírez D, Ramírez MM. Traumatismo craneoencefálico en niños: relación entre los hallazgos tomográficos y el pronóstico. Revista de Especialidades Médico-Quirúrgicas. 2008; 13 (2): 60-8.
[13] Escobedo LVS, Habboushe J, Kaafarani H, Velmahos G, Shah K, Lee J. Traumatic brain injury: A case-based review. World. 2013; 4 (4): 252-9.
[14] Oliveros-Juste A, Bertol V, Oliveros-Cid A. Tratamiento preventivo-profiláctico de la epilepsia postraumática. Revista de Neurología. 2002; 34 (5): 448-59.
[15] Organización Panamericana de la Salud. Clasificacin estadistica internacional de enfermedades y problemas relacionados con la salud. 10ª. Revision. Washington, D.C.: OPS, 1995.
[16] Bayir H, Kochanek PM, Clark RS. Traumatic brain injury in infants and children. Mechanisms of secondary damage and treatment in the intensive care unit. Crit Care Clin 2003; 19: 529-49.
[17] Chun-Chieh Yeh, Ta-Liang Chen, Chaur-Jong Hu, Wen-Ta Chiu, Chien-Chang Liao. Risk of epilepsy after traumatic brain ingury: a retrospective population-based cohory study. J Neurol Neurosurg Psychiatry 2013; 84: 441–445.
[18] Deheza GC, Sierra ML, Lafuente-Riverola VH, Ríos JCV. Análisis clínico-epidemiológico de la presentación y evolución del traumatismo craneoencefálico, en niños menores de 15 años en el HNMAV. Luz y Vida: Revista Médico-Científica. 2012; 3 (1): 36-41.
[19] Centers for Disease Control and Prevention. (2012) Traumatic brain injury in the United States: emergency department visits, Hospitalizations, and deaths, 2002–2006.
[20] Di Luca DG, de Lacerda GCB. Time Interval Between Traumatic Brain Injury And Post Traumatic Epilepsy.
[21] Rodríguez L, Quispe Y, Sifuentes J. Factores de riesgo de epilepsia secundaria en niños. Revista de Neuro-Psiquiatría. 2013; 65 (2): 136-41.
[22] Hunt RF, Boychuk JA, Smith BN. Neural circuit mechanisms of post–traumatic epilepsy. Frontiers in cellular neuroscience. 2013; 7.
[23] López-Pisón J, Arana T, Abenia P, Muñoz Albillos M, Rebage V. Casuística de epilepsia sintomática en una unidad de neuropediatría de referencia regional. Rev Neurol. 2001; 32: 118-22.
Cite This Article
  • APA Style

    Olga Bastidas-Rangel, Imelda Peraza-Gregor, Maria Valeria Jimenez-Baez, Carlos Sanchez-Flores, Luis Sandoval-Jurado. (2022). Post-Traumatic Epilepsy: A Review of This Pathology in Childhood. International Journal of Clinical and Experimental Medical Sciences, 8(4), 50-55. https://doi.org/10.11648/j.ijcems.20220804.11

    Copy | Download

    ACS Style

    Olga Bastidas-Rangel; Imelda Peraza-Gregor; Maria Valeria Jimenez-Baez; Carlos Sanchez-Flores; Luis Sandoval-Jurado. Post-Traumatic Epilepsy: A Review of This Pathology in Childhood. Int. J. Clin. Exp. Med. Sci. 2022, 8(4), 50-55. doi: 10.11648/j.ijcems.20220804.11

    Copy | Download

    AMA Style

    Olga Bastidas-Rangel, Imelda Peraza-Gregor, Maria Valeria Jimenez-Baez, Carlos Sanchez-Flores, Luis Sandoval-Jurado. Post-Traumatic Epilepsy: A Review of This Pathology in Childhood. Int J Clin Exp Med Sci. 2022;8(4):50-55. doi: 10.11648/j.ijcems.20220804.11

    Copy | Download

  • @article{10.11648/j.ijcems.20220804.11,
      author = {Olga Bastidas-Rangel and Imelda Peraza-Gregor and Maria Valeria Jimenez-Baez and Carlos Sanchez-Flores and Luis Sandoval-Jurado},
      title = {Post-Traumatic Epilepsy: A Review of This Pathology in Childhood},
      journal = {International Journal of Clinical and Experimental Medical Sciences},
      volume = {8},
      number = {4},
      pages = {50-55},
      doi = {10.11648/j.ijcems.20220804.11},
      url = {https://doi.org/10.11648/j.ijcems.20220804.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20220804.11},
      abstract = {Introduction: Traumatic brain injury has been related to the 20% of symptomatic epilepsy in the general population; In children, information about the magnitude of this condition is few, because the occurrence can develop in immediate periods or even years after the injury. Objective: To evaluate the epidemiological and clinical characteristics in pediatric patients diagnosed with Post-Traumatic Epilepsy. Methods: Children's Records diagnosed with post-traumatic epilepsy from the Pediatric Neurology Service. The clinical-epidemiological characteristics of the trauma, the convulsive crisis and the latency period in its presentation were identified. The difference of quantitative variables was estimated to evaluate their association, according to the intensity of the Head Traumatism (TBI). Results: 72 children with an average age of 8.7 years and males predominance of with 65.3% were included. The most frequent traumatic brain injury site (TBI) was occipital with 35.6% and the classification was 47.6% for mild. 93.1% presented simple partial crisis and 73.6% of children had neurological sequelae. The median onset for the epileptic seizure was 2.9 years, this period being shorter in relation to the intensity of the trauma and the age group in which it occurs. Conclusions: There is a clinical correlation between the intensity of TBI with the acute presence of epilepsy. It is necessary for the community of neurologists to develop follow-up protocols focused on informing and providing adequate care to patients at high risk of presenting post-traumatic epilepsy, including providing information to parents in a timely manner of this risk considering the intensity of the TBI and without ruling out those who suffered mild TBI.},
     year = {2022}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Post-Traumatic Epilepsy: A Review of This Pathology in Childhood
    AU  - Olga Bastidas-Rangel
    AU  - Imelda Peraza-Gregor
    AU  - Maria Valeria Jimenez-Baez
    AU  - Carlos Sanchez-Flores
    AU  - Luis Sandoval-Jurado
    Y1  - 2022/07/13
    PY  - 2022
    N1  - https://doi.org/10.11648/j.ijcems.20220804.11
    DO  - 10.11648/j.ijcems.20220804.11
    T2  - International Journal of Clinical and Experimental Medical Sciences
    JF  - International Journal of Clinical and Experimental Medical Sciences
    JO  - International Journal of Clinical and Experimental Medical Sciences
    SP  - 50
    EP  - 55
    PB  - Science Publishing Group
    SN  - 2469-8032
    UR  - https://doi.org/10.11648/j.ijcems.20220804.11
    AB  - Introduction: Traumatic brain injury has been related to the 20% of symptomatic epilepsy in the general population; In children, information about the magnitude of this condition is few, because the occurrence can develop in immediate periods or even years after the injury. Objective: To evaluate the epidemiological and clinical characteristics in pediatric patients diagnosed with Post-Traumatic Epilepsy. Methods: Children's Records diagnosed with post-traumatic epilepsy from the Pediatric Neurology Service. The clinical-epidemiological characteristics of the trauma, the convulsive crisis and the latency period in its presentation were identified. The difference of quantitative variables was estimated to evaluate their association, according to the intensity of the Head Traumatism (TBI). Results: 72 children with an average age of 8.7 years and males predominance of with 65.3% were included. The most frequent traumatic brain injury site (TBI) was occipital with 35.6% and the classification was 47.6% for mild. 93.1% presented simple partial crisis and 73.6% of children had neurological sequelae. The median onset for the epileptic seizure was 2.9 years, this period being shorter in relation to the intensity of the trauma and the age group in which it occurs. Conclusions: There is a clinical correlation between the intensity of TBI with the acute presence of epilepsy. It is necessary for the community of neurologists to develop follow-up protocols focused on informing and providing adequate care to patients at high risk of presenting post-traumatic epilepsy, including providing information to parents in a timely manner of this risk considering the intensity of the TBI and without ruling out those who suffered mild TBI.
    VL  - 8
    IS  - 4
    ER  - 

    Copy | Download

Author Information
  • Regional General Hospital No. 17. Mexican Institute of Social Security Cancun, Cancun, Mexico

  • Family Medicine Unit No. 16, Mexican Institute of Social Security, Cancun, Mexico

  • Head of Medical Benefits, Mexican Social Security Institute, Cancun, Mexico

  • Pediatric Neurology Consultation, Cancun, Mexico

  • Head of Medical Benefits, Mexican Social Security Institute, Cancun, Mexico

  • Sections