| Peer-Reviewed

Progress in Research Contents and Methods of Theoretical Toxicology

Received: 24 February 2019     Accepted: 2 April 2019     Published: 22 April 2019
Views:       Downloads:
Abstract

Toxicology is a modern science. Because of the rapid development of industry and agriculture, the amount of chemicals increases explosively. There has been more than 26,000,000 chemicals registered in the world and over 2000 new chemicals are produced every year. Therefore the traditional methods of toxicological evaluation cannot meet the requirements in the modern society, let alone the precise toxicological study for various chemicals. It is needed to make innovation in theory, so as to shorten the period, reduce the expenditure and input in the research, which may make the applications of chemicals safer. Meanwhile, as animal welfare is putting on the public agenda, less animals will be permitted to be used largely in the toxicological research. All of these promote the development of theoretical toxicology.

Published in International Journal of Clinical and Experimental Medical Sciences (Volume 5, Issue 1)
DOI 10.11648/j.ijcems.20190501.13
Page(s) 10-13
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Theoretical Toxicology, Big Data Processing, Cloud Computing

References
[1] Zuang shi-xion. The development and prospect of toxicology in China. Chinese journal of preventive medicine 2008, 42 (s):9-10.
[2] Jiang yun-shen, Zhou jian-wei. Future toxicology---Quantum toxicology Chin J ind hyg occup dis 2014, 32(11)10-12.
[3] Wang xing. Big data analysis: methods and applications.. Beijing Tsinghua university press 2013, 1-4.
[4] Wang peng: Approaching cloud computing People's post and telecommunications publishing house Beijing 2009:1-2.
[5] Peleg Y, Pnini R, Zaaruru E. et al. Quantum mechanics.. Schuam's outline series 2nd. [M]. New York. Mcgrew hill company, 2010:21-40.
[6] Kanno J,: Reverse toxicology as a future predictive toxicology [M] Inoue T, Rennie W D:Toxicologenomics. Tokyo: Springer-verlag. Tokyo. Inc. 2003:213-218.
[7] Zhu yon-liang, Ye zu-guang: Advance in computational toxicology and prediction of toxicity of Chinese meteria medica. Chin J new drugs 2011, 20(24):2424-2429.
[8] Xie ying, Wu jian-guo, Li wei et al: Toxicity prediction of unknown compounds based on gspan algorithm. Journal of Hefei university of technology. natural science edition 2007, 30(10):1278-1280.
[9] Wang jian-suo, Lai lu--hua, Tang you-qi:Prediction toxicology and database excavation of compounds. Chinese science bulletin 2000, 45(4):360-364.
[10] Wang bin, Yugang, Zhang zu-lin: Quantitative structure activity relationship and joint toxicity prediction of alkyl alcohos. Chinese science bulletin 2006, 51(13):1513-1518.
[11] Liu yang, Wang yon-hua, Li yen:calculation and prediction of environmental carcinogens. Journal of molecular science 2008, 24(6):393-398.
[12] Cao jia, Zheng yu-xin Zhou zon-can: Progress and hotspots in toxicology. China science foundation 2011(3):138-147.
[13] Li hon, Wang chon-jun,: Application of bioinformatics in the toxicogenomics research. Journal of Bioinformatics.2010, 8(4):330-333.
[14] Dai yu-fei, Zheng yu-xin:Reexamination of the central principle of toxicology--doseresponse relationship of toxicant stimulation and it's impact on toxicology development. J of Foreign medical sciences(section of hygiene)2003, 30(4):246-249.
[15] John Paul Gosling: The importance of mathematical modelling in chemical risk assessment and the associated quantification of uncertainty. Computational toxicology 2019 10 44-50.
Cite This Article
  • APA Style

    Yunshen Jiang. (2019). Progress in Research Contents and Methods of Theoretical Toxicology. International Journal of Clinical and Experimental Medical Sciences, 5(1), 10-13. https://doi.org/10.11648/j.ijcems.20190501.13

    Copy | Download

    ACS Style

    Yunshen Jiang. Progress in Research Contents and Methods of Theoretical Toxicology. Int. J. Clin. Exp. Med. Sci. 2019, 5(1), 10-13. doi: 10.11648/j.ijcems.20190501.13

    Copy | Download

    AMA Style

    Yunshen Jiang. Progress in Research Contents and Methods of Theoretical Toxicology. Int J Clin Exp Med Sci. 2019;5(1):10-13. doi: 10.11648/j.ijcems.20190501.13

    Copy | Download

  • @article{10.11648/j.ijcems.20190501.13,
      author = {Yunshen Jiang},
      title = {Progress in Research Contents and Methods of Theoretical Toxicology},
      journal = {International Journal of Clinical and Experimental Medical Sciences},
      volume = {5},
      number = {1},
      pages = {10-13},
      doi = {10.11648/j.ijcems.20190501.13},
      url = {https://doi.org/10.11648/j.ijcems.20190501.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20190501.13},
      abstract = {Toxicology is a modern science. Because of the rapid development of industry and agriculture, the amount of chemicals increases explosively. There has been more than 26,000,000 chemicals registered in the world and over 2000 new chemicals are produced every year. Therefore the traditional methods of toxicological evaluation cannot meet the requirements in the modern society, let alone the precise toxicological study for various chemicals. It is needed to make innovation in theory, so as to shorten the period, reduce the expenditure and input in the research, which may make the applications of chemicals safer. Meanwhile, as animal welfare is putting on the public agenda, less animals will be permitted to be used largely in the toxicological research. All of these promote the development of theoretical toxicology.},
     year = {2019}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Progress in Research Contents and Methods of Theoretical Toxicology
    AU  - Yunshen Jiang
    Y1  - 2019/04/22
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ijcems.20190501.13
    DO  - 10.11648/j.ijcems.20190501.13
    T2  - International Journal of Clinical and Experimental Medical Sciences
    JF  - International Journal of Clinical and Experimental Medical Sciences
    JO  - International Journal of Clinical and Experimental Medical Sciences
    SP  - 10
    EP  - 13
    PB  - Science Publishing Group
    SN  - 2469-8032
    UR  - https://doi.org/10.11648/j.ijcems.20190501.13
    AB  - Toxicology is a modern science. Because of the rapid development of industry and agriculture, the amount of chemicals increases explosively. There has been more than 26,000,000 chemicals registered in the world and over 2000 new chemicals are produced every year. Therefore the traditional methods of toxicological evaluation cannot meet the requirements in the modern society, let alone the precise toxicological study for various chemicals. It is needed to make innovation in theory, so as to shorten the period, reduce the expenditure and input in the research, which may make the applications of chemicals safer. Meanwhile, as animal welfare is putting on the public agenda, less animals will be permitted to be used largely in the toxicological research. All of these promote the development of theoretical toxicology.
    VL  - 5
    IS  - 1
    ER  - 

    Copy | Download

Author Information
  • Department of Toxicology, Nanjing Medical University, Nanjing, China

  • Sections