| Peer-Reviewed

A Rare Case of POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome with the Isolated Adrenal Tuberculosis

Received: 17 January 2018     Accepted: 2 February 2018     Published: 23 February 2018
Views:       Downloads:
Abstract

POEMS syndrome is a rare paraneoplastic syndrome characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. The diagnosis of this disease is often challenging due to its rarity and its multisystemic involvement. Isolated adrenal tuberculosis is also a rare disease which is also difficult to diagnose. Therefore it is incredibly challenging to diagnose a patient with POEMS syndrome when he has isolated adrenal tuberculosis. In this report, we describe a 43-year-old man suffering from POEMS syndrome with right adrenal tuberculosis. His symptoms were very complicated and initially we misdiagnosed him with endocrinal disturbances and the adverse effects of antituberculosis drugs. It was not until we accumulated enough evidences of POEMS syndrome that we could make the final diagnosis. To the best of our knowledge, this is the first report of POEMS syndrome with isolated adrenal tuberculosis.

Published in International Journal of Clinical and Experimental Medical Sciences (Volume 4, Issue 1)
DOI 10.11648/j.ijcems.20180401.13
Page(s) 14-17
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

POEMS Syndrome, The Isolated Adrenal Tuberculosis, Diagnosis

References
[1] Dao L N, Hanson C A, Angela D, et al. Bone marrow histopathology in POEMS syndrome: a distinctive combination of plasma cell, lymphoid, and myeloid findings in 87 patients. Blood 2011; 117(24):6438-44.
[2] Dispenzieri A. POEMS Syndrome (Takatsuki Syndrome). Multiple Myeloma. Springer New York 2014;179-193.
[3] Resnick D, Greenway G D, Bardwick P A, et al. Plasma-cell dyscrasia withpolyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes: the POEMS syndrome. Distinctive radiographic abnormalities. Radiology 1981;140(1):17-22.
[4] Takatsuki K, Sanada I,. Plasma cell dyscrasia with polyneuropathy and endocrine disorder: clinical and laboratory features of 109 reported cases. Japanese Journal of Clinical Oncology 1983; 13(3):543-55.
[5] Crow R S. Peripheral Neuritis in Myelomatosis. British Medical Journal 1956;2(4996):802-804.
[6] Fukase M, Kakimatsu T, Nishitani H, et al. Report of a case of solitary plasmacytoma in the abdomen presenting polyneuropathy and endocrinological disorders. Clin Neurol (Tokyo).1969;9:657.
[7] Nasu S, Misawa S, Sekiguchi Y, et al. Different neurological and physiological profiles in POEMS syndrome and chronic inflammatory demyelinating polyneuropathy. Journal of Neurology Neurosurgery & Psychiatry 2012;83(5):476-479.
[8] Angela D. How I treat POEMS syndrome. Blood 2012;119(24):5650-8.
[9] Lam K Y, Lo C Y. A critical examination of adrenal tuberculosis and a 28-year autopsy experience of active tuberculosis. Clinical Endocrinology 2001;54(5):633-39.
[10] Joshi A R, Basantani A S, Patel T C. Role of CT and MRI in Abdominal Tuberculosis. Current Radiology Reports 2014;2(10):1-16.
[11] Taku M, Hiroyuki S, Kotaro H, et al. [Unilateral adrenal tuberculosis: a case report. Hinyokika Kiyo Acta Urologica Japonica 2014;60(12):611-4.
[12] Dispenzieri A. POEMS syndrome: 2014 Update on diagnosis, risk‐stratification, and management. American journal of hematology 2014;89(2): 213-23.
[13] Briani C, Lucchetta M, Scarlato M. POEMS Syndrome. Encyclopedia of the Neurological Sciences 2014;35(8):912-14.
Cite This Article
  • APA Style

    Li Tian, Xuewen Xiao, Yang Cao, Jingbo Li, Shourong Shen, et al. (2018). A Rare Case of POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome with the Isolated Adrenal Tuberculosis. International Journal of Clinical and Experimental Medical Sciences, 4(1), 14-17. https://doi.org/10.11648/j.ijcems.20180401.13

    Copy | Download

    ACS Style

    Li Tian; Xuewen Xiao; Yang Cao; Jingbo Li; Shourong Shen, et al. A Rare Case of POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome with the Isolated Adrenal Tuberculosis. Int. J. Clin. Exp. Med. Sci. 2018, 4(1), 14-17. doi: 10.11648/j.ijcems.20180401.13

    Copy | Download

    AMA Style

    Li Tian, Xuewen Xiao, Yang Cao, Jingbo Li, Shourong Shen, et al. A Rare Case of POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome with the Isolated Adrenal Tuberculosis. Int J Clin Exp Med Sci. 2018;4(1):14-17. doi: 10.11648/j.ijcems.20180401.13

    Copy | Download

  • @article{10.11648/j.ijcems.20180401.13,
      author = {Li Tian and Xuewen Xiao and Yang Cao and Jingbo Li and Shourong Shen and Xiaoyan Wang and Anliu Tang and Xiayu Li and Fen Liu and Feiyan Ai},
      title = {A Rare Case of POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome with the Isolated Adrenal Tuberculosis},
      journal = {International Journal of Clinical and Experimental Medical Sciences},
      volume = {4},
      number = {1},
      pages = {14-17},
      doi = {10.11648/j.ijcems.20180401.13},
      url = {https://doi.org/10.11648/j.ijcems.20180401.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20180401.13},
      abstract = {POEMS syndrome is a rare paraneoplastic syndrome characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. The diagnosis of this disease is often challenging due to its rarity and its multisystemic involvement. Isolated adrenal tuberculosis is also a rare disease which is also difficult to diagnose. Therefore it is incredibly challenging to diagnose a patient with POEMS syndrome when he has isolated adrenal tuberculosis. In this report, we describe a 43-year-old man suffering from POEMS syndrome with right adrenal tuberculosis. His symptoms were very complicated and initially we misdiagnosed him with endocrinal disturbances and the adverse effects of antituberculosis drugs. It was not until we accumulated enough evidences of POEMS syndrome that we could make the final diagnosis. To the best of our knowledge, this is the first report of POEMS syndrome with isolated adrenal tuberculosis.},
     year = {2018}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - A Rare Case of POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome with the Isolated Adrenal Tuberculosis
    AU  - Li Tian
    AU  - Xuewen Xiao
    AU  - Yang Cao
    AU  - Jingbo Li
    AU  - Shourong Shen
    AU  - Xiaoyan Wang
    AU  - Anliu Tang
    AU  - Xiayu Li
    AU  - Fen Liu
    AU  - Feiyan Ai
    Y1  - 2018/02/23
    PY  - 2018
    N1  - https://doi.org/10.11648/j.ijcems.20180401.13
    DO  - 10.11648/j.ijcems.20180401.13
    T2  - International Journal of Clinical and Experimental Medical Sciences
    JF  - International Journal of Clinical and Experimental Medical Sciences
    JO  - International Journal of Clinical and Experimental Medical Sciences
    SP  - 14
    EP  - 17
    PB  - Science Publishing Group
    SN  - 2469-8032
    UR  - https://doi.org/10.11648/j.ijcems.20180401.13
    AB  - POEMS syndrome is a rare paraneoplastic syndrome characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. The diagnosis of this disease is often challenging due to its rarity and its multisystemic involvement. Isolated adrenal tuberculosis is also a rare disease which is also difficult to diagnose. Therefore it is incredibly challenging to diagnose a patient with POEMS syndrome when he has isolated adrenal tuberculosis. In this report, we describe a 43-year-old man suffering from POEMS syndrome with right adrenal tuberculosis. His symptoms were very complicated and initially we misdiagnosed him with endocrinal disturbances and the adverse effects of antituberculosis drugs. It was not until we accumulated enough evidences of POEMS syndrome that we could make the final diagnosis. To the best of our knowledge, this is the first report of POEMS syndrome with isolated adrenal tuberculosis.
    VL  - 4
    IS  - 1
    ER  - 

    Copy | Download

Author Information
  • Department of Gastroenterology, The Third Xiangya Hospital, Cental South University, Changsha, China

  • Department of Gastroenterology, The Third Xiangya Hospital, Cental South University, Changsha, China

  • Department of Gastroenterology, The Third Xiangya Hospital, Cental South University, Changsha, China

  • Department of Gastroenterology, The Third Xiangya Hospital, Cental South University, Changsha, China

  • Department of Gastroenterology, The Third Xiangya Hospital, Cental South University, Changsha, China

  • Department of Gastroenterology, The Third Xiangya Hospital, Cental South University, Changsha, China

  • Department of Gastroenterology, The Third Xiangya Hospital, Cental South University, Changsha, China

  • Department of Gastroenterology, The Third Xiangya Hospital, Cental South University, Changsha, China

  • Department of Gastroenterology, The Third Xiangya Hospital, Cental South University, Changsha, China

  • Department of Gastroenterology, The Third Xiangya Hospital, Cental South University, Changsha, China

  • Sections